Predicting initial nucleation events occurred in a metastable nanodroplet during acoustic droplet vaporization
نویسندگان
چکیده
منابع مشابه
Acoustic Droplet Vaporization in Biology and Medicine
This paper reviews the literature regarding the use of acoustic droplet vaporization (ADV) in clinical applications of imaging, embolic therapy, and therapeutic delivery. ADV is a physical process in which the pressure waves of ultrasound induce a phase transition that causes superheated liquid nanodroplets to form gas bubbles. The bubbles provide ultrasonic imaging contrast and other functions...
متن کاملApplication of acoustic droplet vaporization in ultrasound therapy
Microbubbles have been used widely both in the ultrasonic diagnosis to enhance the contrast of vasculature and in ultrasound therapy to increase the bioeffects induced by bubble cavitation. However, due to their large size, the lifetime of microbubbles in the circulation system is on the order of minutes, and they cannot penetrate through the endothelial gap to enter the tumor. In an acoustic f...
متن کاملAcoustic droplet vaporization is initiated by superharmonic focusing.
Acoustically sensitive emulsion droplets composed of a liquid perfluorocarbon have the potential to be a highly efficient system for local drug delivery, embolotherapy, or for tumor imaging. The physical mechanisms underlying the acoustic activation of these phase-change emulsions into a bubbly dispersion, termed acoustic droplet vaporization, have not been well understood. The droplets have a ...
متن کاملTheranostic Performance of Acoustic Nanodroplet Vaporization-Generated Bubbles in Tumor Intertissue
Solid tumors with poorly perfused regions reveal some of the treatment limitations that restrict drug delivery and therapeutic efficacy. Acoustic droplet vaporization (ADV) has been applied to directly disrupt vessels and release nanodroplets, ADV-generated bubbles (ADV-Bs), and drugs into tumor tissue. In this study, we investigated the in vivo behavior of ADV-Bs stimulated by US, and evaluate...
متن کاملCompetitive nucleation in metastable systems
Metastability is observed when a physical system is close to a first order phase transition. In this paper the metastable behavior of a two state reversible probabilistic cellular automaton with self–interaction is discussed. Depending on the self–interaction, competing metastable states arise and a behavior very similar to that of the three state Blume–Capel spin model is found.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Ultrasonics Sonochemistry
سال: 2021
ISSN: 1350-4177
DOI: 10.1016/j.ultsonch.2021.105608